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Specific HIV Medication Interactions
General
- ARV Alert (Regularly Updated)
Periodic updates on newly announced interactions involving HIV medications; each update features a brief synopsis of the interaction, as well as a chart outlining key information.
From HIV InSite
- Patient Information About Reyataz (Atazanavir) (PDF) (December 2007)
From Bristol-Myers Squibb Company
- Acid-Reducing Agents Reduce Atazanavir Drug Levels but Not Lopinavir/Ritonavir Levels (February 7, 2006)
In The 13th Conference on Retroviruses and Opportunistic Infections
- French Study Questions Interaction Between Atazanavir and Antacids (October 24, 2005)
From aidsmap.com
- ddI + Ribavirin May Cause Mitochondrial Toxicity (September 1, 2005)
In Journal of Acquired Immune Deficiency Syndromes
- Efavirenz Reduces Plasma Levels of Popular Statins (July/August 2005)
From The Body PRO
- Antacids and HIV Medications (May/June 2005)
Over-the-counter antacids like Mylanta, Rolaids and Tums can decrease blood levels of some HIV meds.
In Survival News, from AIDS Survival Project
- Notice of Important New Drug Interactions With Norvir, Kaletra (March 30, 2005)
New interactions noted with fluticasone (a component of Flonase nasal spray) and trazodone (Desyrel, an antidepressant).
From U.S. Food and Drug Administration
- Drug Interaction Warning: Saquinavir/Ritonavir and Rifampin (Rifampicin, Rifadin, Rimactane, Rofact) (February 8, 2005)
To read PDF, click here
From U.S. Food and Drug Administration
- Don't Combine Fosamprenavir and Lopinavir/Ritonavir (February/March 2005)
From The Body PRO
- Do Not Combine Reyataz and Prilosec: News Summary (December 31, 2004)
In AIDS Treatment News, from AIDS Treatment News
- Atazanavir, With or Without Ritonavir, Should Not Be Coadministered With Proton Pump Inhibitors (December 20, 2004)
From U.S. Food and Drug Administration
- Warning Against Using Erythromycin (Even Orally) While Using Protease Inhibitors or Certain Other Drugs (October 26, 2004)
A study finds an increased risk of sudden death from cardiac causes.
In AIDS Treatment News, from AIDS Treatment News
- ddI + Tenofovir Combination Linked to Higher Pancreatitis Risk (October 2004)
Quick recap of a report in The Lancet.
In HIV Treatment ALERTS!, from The Center for AIDS
- Interaction Reported Between Grapefruit Juice and Statins (October 2004)
This interaction may also worsen other interactions between statins and HIV medications.
In HIV Treatment ALERTS!, from The Center for AIDS
- News on Developing Drugs and Drug Interactions (September/October 2004)
Updates on tipranavir, GS 9005 and the interaction between ddI and tenofovir.
In GMHC Treatment Issues, from Gay Men's Health Crisis
- Genetics Influence Response to HAART and Incidence of Pancreatitis, Studies Show (August 3, 2004)
From aidsmap.com
- Changes to Labeling for Desyrel (Trazodone Hydrochloride) Tablets (PDF) (May 2004)
A "Dear Healthcare Professional" letter on potential interactions between this antidepressant and CYP3A4 inhibitors such as indinavir and ritonavir.
From U.S. Food and Drug Administration
- Non-Antiretroviral Medication-Related Adverse Events During Treatment of HIV-Related Infections and Complications (May 2004)
From HIV InSite
- Atazanavir (Reyataz): New Recommendations if Combined With Tenofovir (Viread) -- and Warning on Viagra, Cialis, and Levitra (March 26, 2004)
New warnings on drug-drug interactions are noted in the prescribing information for atazanavir.
In AIDS Treatment News, from AIDS Treatment News
- Atazanavir/Tenofovir Combo Should Be Boosted With Ritonavir (August 8, 2003)
From U.S. Food and Drug Administration
- HIV-Positive Man Dies of Kidney Failure and Lactic Acidosis Due to Tenofovir/ddI Interaction (April 8, 2003)
From aidsmap.com
- Herbs, Supplements and HIV: Drug Interactions (April 2003)
To read PDF, click here
From Project Inform
- Tenofovir DF and Didanosine EC: Investigation of Pharmacokinetic Drug-Drug and Drug-Food Interactions (November 21, 2002)
In The 6th International Congress on Drug Therapy in HIV Infection, from The Body PRO
- Intracellular Metabolism of AZT Leads to the Production of Significant Levels of d4T Triphosphate in HIV Infected Patients (November 19, 2002)
In The 6th International Congress on Drug Therapy in HIV Infection, from The Body PRO
- New Safety Information -- Viread Co-Administration With Videx (September 30, 2002)
From U.S. Food and Drug Administration
- Viread-Videx EC Drug Interactions -- What's a Person to Do? (Fall 2002)
To read PDF, click here
In STEP Perspective, from Seattle Treatment Education Project
- New Safety Information for Videx (Didanosine, ddI) Used With Ribavirin (September 25, 2002)
From U.S. Food and Drug Administration
- FDA Bits: 3TC, Amprenavir and Nandrolone (September 2002)
Once-a-day dosing for 3TC (Epivir) approved; new interaction warnings for amprenavir (Agenerase); nandrolone decanoate returns to the U.S. market.
In HIV Treatment ALERTS!, from The Center for AIDS
- Drug Interactions Need More Attention (January 25, 2002)
To read PDF, click here
In AIDS Treatment News, from AIDS Treatment News
- Caution With Nelfinavir and Some Lipid-Lowering Drugs (November 21, 2001)
From Canadian AIDS Treatment Information Exchange
- Bizarre Side Effects From an Interaction Between Nevirapine and Clarithromycin (August 17, 2001)
From Canadian AIDS Treatment Information Exchange
- Women and Pharmacology (March 2001)
To read PDF, click here
In Project Inform Perspective, from Project Inform
- Risk of Interactions Between Zyban & HAART (March 5, 2001)
From aidsmap.com
- Drug Transporter, Drug Concentrations, and Drug Interactions (March 1, 2001)
In Hopkins HIV Report
- Drug Interactions of Protease Inhibitors and Psychiatric Medications (January 2001)
In Survival News, from AIDS Survival Project
- Caution Advised When Using Cipro With Methadone (December 20, 2000)
From Canadian AIDS Treatment Information Exchange
- Methadone Interferes With Some Formulations of ddI (September 8, 2000)
From Canadian AIDS Treatment Information Exchange
- Protease Inhibitors Interact With Some Sleeping Pills (August 31, 2000)
From Canadian AIDS Treatment Information Exchange
- Ritonavir and PI-Boosting: Using Drug/Drug Interactions to Our Advantage (July 14, 2000)
In STEP Ezine, from Seattle Treatment Education Project
- Selected Highlights From the 7th CROI: Drug Interaction and Side Effect Studies (Spring 2000)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- What You Should Know About Mixing Cocktails (Spring 2000)
In STEP Perspective, from Seattle Treatment Education Project
- Drug Interaction and the Anti-HIV Drug Emivirine (Coactinon) (December 1999)
From Project Inform
- Drug Interactions Studied at ICAAC (November 1999)
In Positive Living, from AIDS Project Los Angeles
- FDA Strengthens Warning Label for Propulsid (June 29, 1998)
Heartburn drug may interact with protease inhibitors.
From U.S. Food and Drug Administration
- Efavirenz (Sustiva, DMP 266) and Saquinavir (Fortovase) Combination: Pharmacologic Interaction (June 5, 1998)
From AIDS Treatment News
- Drug Interactions Associated With Protease Inhibitors (May 1998)
In Positive Living, from AIDS Project Los Angeles
- Drug Interactions: Another Complication in HIV Care (April 1998)
In Positive Living, from AIDS Project Los Angeles
- Drug Interactions: Resources for Patients and Professionals (March 6, 1998)
In AIDS Treatment News, from AIDS Treatment News
- Drugs That May Interact With Protease Inhibitors via CYP3A4 Metabolism (December 18, 1997)
In Protease Inhibitors Backgrounder, from U.S. Food and Drug Administration
- Effects of Protease Inhibitors and Other Commonly Used Medications as Determined by Drug Interaction Studies (December 18, 1997)
In Protease Inhibitors Backgrounder, from U.S. Food and Drug Administration
- Medications That Should Not Be Used With Protease Inhibitors (December 18, 1997)
In Protease Inhibitors Backgrounder, from U.S. Food and Drug Administration
- Protease Inhibitor Drug Interactions: What Do Patients Need to Know? (August 27, 1997)
An edited transcript of a BETA Live! conference call broadcast.
From San Francisco AIDS Foundation
- Book Review of "Powers and Moore's Food-Medications Interactions" (May 1997)
In Journal of the International Association of Physicians in AIDS Care, from International Association of Physicians in AIDS Care
- Medications Contraindicated With the Use of Ritonavir (April 3, 1996)
In TAGline, from Treatment Action Group
St. John's Wort
Viagra
Cholesterol-Lowering Medications (Statins)
Birth Control Pills
Vitamins
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