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Somatropin
soe-ma-TROE-pin   Audio

Brand Name: Genotropin, Serostim  Audio
Drug Class: Opportunistic Infection and Other Drugs
Somatropin, also known as Genotropin or Serostim, is a type of medicine called a synthetic human growth hormone. It is a man-made version of growth hormone, a substance that stimulates growth of the long bones in the arms and legs by affecting growth of cartilage, bone, and muscle cells. It also increases the size of body organs and increases the number of red blood cells.

HIV/AIDS-Related Uses
Somatropin was approved by the FDA on August 23, 1996, for use with antiretroviral agents in the treatment of wasting syndrome (progressive and unintended loss of more than 10% of body weight) in HIV infection. Somatropin is being studied in HIV infected patients to see if it can improve the body's immune response and slow the progress of HIV infection.
This medicine does not cure or prevent HIV infection or AIDS and does not reduce the risk of passing the virus to other people.

Dosage Form/Administration
Somatropin comes in powder form that is mixed with diluent and is injected under the skin.


Contraindications
Individuals should tell a doctor about any medical problems before taking this medicine.

Possible Side Effects
Along with its desired effects, somatropin can cause some unwanted effects. Serious side effects of this medicine include ear disorders; skin rash or itching; changes in vision; headache, nausea, and vomiting; swelling of optic nerve; pain and swelling at site of injection; abdominal pain or swelling of the stomach; and limp or pain in hip or knees. Individuals should tell a doctor if they have symptoms of any of these side effects.
Other side effects may not be serious and may lessen or disappear with continued use of the medicine. Less serious side effects of this medicine include mild but temporary wrist pain; enlargement of breasts; increased growth of birthmarks; joint pain or muscle pain; swelling of hands, feet, or lower legs; and unusual tiredness or weakness. Individuals should tell a doctor if these side effects continue or are bothersome.

Drug and Food Interactions
A doctor should be notified of any other medications being taken, including prescription, nonprescription (over-the-counter), or herbal medications.

Clinical Trials
Click here to search ClinicalTrials.gov for trials that use Somatropin.

Manufacturer Information
Somatropin
  Serono Inc.
  One Technology Place
  Rockland,  MA  02370
  (800) 283-8088
    

Serostim
  Serono Inc.
  One Technology Place
  Rockland,  MA  02370
  (800) 283-8088
    

Genotropin
  Pharmacia Corporation
  100 Route 206 North
  Peapack,  NJ  07977
  (888) 768-5501
    
Updated March 7, 2008