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Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.

The participation of Dr. McGovern in this Forum is made possible in part by an independent educational grant from Roche Laboratories.

Ask the Experts about Hepatitis and HIV Coinfection
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Query Follow up
Aug 25, 2008

Dear doctors,I have sent u some Heb B results almost a week ago for interpretation but havent recieved any reply yet.I was on Zeffix for a year wherein my HBeAg became negative on my 3rd month of treatment but was advised by d doctor to have it only for a year.3-4 months POST Zeffix,HBeAg again positive.I would be grateful if u will be able 2 help me out with my latest results as follows; HBsAg positive, HBeAg positive,ALT 33 IU/L ,HBV DNA PCR 73 IU/ml.Im finishing my one year of Hepsera therapy this month.Thanks

Response from Dr. McGovern

I would continue treatment since if you stop - your virus will certainly come back. I only stop treatment six months after the patient has developed HBe antibodies. You are still HBeAg+ so you continue to need treatment to get viral suppression. You are almost there.



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